Tonics for the blood in China have a long history.

Dang gui bu xue tang: Even though DBT has been demonstrated to have anti-oxidant, estrogenic, hematopoietic and immunogenic properties, its role in cellular energy metabolism has yet to be determined. Traditionally, Dang Gui has been utilized to assist women in achieving, supporting, and maintaining regular menstrual cycles. As a sedative, it also possesses analgesic properties.

Introduction:

When it comes to Chinese herbs, Dang Gui is one of the most regularly used. Although it is commonly referred to as a “women’s herb,” many males also use it. Among its many benefits is its reputation as a potent blood tonic, which accounts for much of the herb’s popularity among women. Also known as a “blood vitalizer,” it promotes healthy circulation throughout the body, particularly in the abdominal and pelvic regions. B

Pharmacological effects of DBT:

As a treatment for menopausal symptoms, DBT is now recommended to be taken on an everyday basis. Both in vitro and in vivo studies of DBT’s pharmacological effects have been conducted. Numerous animal studies have shown that Dang Gui Bu Xue Tang can raise the number of red and white blood cells, activate estrogenic properties, increase bone regeneration, trigger immunological responses, and encourage the formation of capillaries and blood vessels.

Tonics for the blood in China have a long history:

It is the root of the Chinese angelica plant in China known as Dang Gui, or Dong Gui or Dong Quai. It is found as a perennial plant on the shores of rivers and oceans and ravines and gorges. Traditional Asian herbal treatments have long used Dang Gui root, one of the Chinese blood tonics.

Background:

Li Dongyuan penned the Neiwaishang Bianhuo Lun in AD 1247, where he first described DBT. DBT has traditionally been used to increase “Blood” and “Qi” flow. Menopause symptoms can alleviate with DBT, which is now recommended as a daily treatment.

Methods:

In this study, the roots of Astragalus Membranaceus var. Mongolic (AR) and Angelica Sinensis (ASR) were harvested at three and two years, respectively. Dr. Tina Dong carried out the microscope identifications and validated the raw materials using the analysis indicated in the China Pharmacopeia. ASR and AR were carefully weighted to a ratio of 1:5 to create the DBT formula.

Chromatogram showing DBT’s fingerprints:

Vehicle, binary pumps, solvent evaporation, and a tribal column compartment were all included in this chemical fingerprint investigation using Agilent 1200 series equipment.  An Agilent, Eclipse Plus as employed for chromatographic conditions. The flow rate is constant at 1.0 mL/min at room temperature using nitrile (as Solvent A) and 0.1 percent formic acid (as Solvent B) (as Solvent B).

Developing a DBT chemical standard:

Chemical standardization is a crucial step in ensuring that biological studies are repeatable and consistent. Both ELSD and DAD detectors were used to study the chromatographic conditions of DBT, as previously reported. It should include 809 micrograms of ASR-derived ferulic acid and 220 micrograms of Z-ibutilide, and 693 micrograms of calycosin.

DBT can induce neurotrophic factor expressions:

Neurotrophic factors such as NGF, BDNF, and GDNF are critical for neurons’ survival, development, and differentiation. Neurotrophic factors deficiency can lead to a variety of neurological illnesses. SH-SY5Y cells were grown, and NGF, BDNF, and GDNF protein expressions were measured.

Benefits of dang gui bu xue tang:

Menopausal symptoms such as hot flashes, mood swings, headaches, and others can alleviate this remedy. As a bonus benefit, its capacity to enhance circulation makes it ideal for use during the healing process following a medical condition or injury. The herbs were thoroughly combined before being cooked twice in water. After being lyophilized and suspended, the water extract was used to perform the biological experiment.

Discussion:

Traditional Chinese Medicine (TCM) posits that the combination of herbs enhances the therapeutic efficacy of a single herb by their compatibility. As a treatment for menopausal symptoms, DBT has traditionally been suggested.

Quality of dang gui bu xue tang:

Selecting Dang Gui is a serious question of quality. From Asia, this plant is available in a wide range of grades. It’s one of those herbs that people pick out with great care and become experts on. For more than three decades, Ron Teeguarden has been procuring Dang Gui. Dragon’s Herbs Dang Gui comes from a valley in northwest China that has long been revered as a primary Di Tao source for this particular variety of tea.

Roots that are freshly harvested:

The freshly harvested roots are used to make our Dang Gui, which has a deep, sweet aroma and an ideal mix of ingredients. Phytoestrogens, botanical compounds that mimic the effects of estrogen, are also found in Dang Gui. It can use during the menstrual cycle and during menopause and perimenopause to regulate female hormone levels.

Odor:

It has a musky odor that’s strong yet not overpowering. Using this herb will not only nourish the body, but it will also disperse blood throughout the body, resulting in a radiant complexion, luscious hair, and a calm mind, according to Chinese thought. Chemical standardization ensured the quality of DBT manufactured under optimal conditions.

Muscle glycogen and glycolysis are affected by DBT:

We found that the 21-day training regimen did not significantly improve muscular strength or endurance performance with no supplementation. According to earlier research, these findings were consistent. There was no difference in forelimb grip strength and exhaustion time between the inactive and trained mice after a 42-day swimming program with incremental loading of 3–35 percent bodyweight.

DBT treatment:

A metabolomics technique was used in another study to look at the effects of DBT on fatigued mice. After Dang Gui Bu Xue Tang treatment, pyruvate and lactate in the glycolytic pathway were decreased, whereas citric acid in the Krebs cycle was increased. According to this, DBT may improve mitochondrial activity and ATP production by altering node metabolites and metabolic pathway networks.

Conclusions:

In this study, researchers concluded that DBT could be an effective sports ergogenic supplement for athletes and other fitness-minded individuals. Future research should focus on identifying the bioactive components that are responsible for the ergogenic effects. As a result, Dang Gui Bu Xue Tang may be useful in treating neurodegenerative disorders, such as Alzheimer’s disease.

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